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Recent publications

2026

Genetic background and immune response in paracoccidioidomycosis: A systematic review and meta-analysis of single nucleotide variants. Coelho SDS, Fava WS, Burger E, Pereira-Latini AC, Pontillo A, Venturini J. PLoS Negl Trop Dis. 2026 Mar 19;20(3):e0014110. doi: 10.1371/journal.pntd.0014110. 

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Neutrophils and the NLRP3 inflammasome: a tale of proteases, kinases, and inflammation. Leal VNC, Weber ANR. J Leukoc Biol. 2026 Feb 9;118(2):qiag008. doi: 10.1093/jleuko/qiag008. 

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Updating the frequency of CCR5Δ32 in Brazil: Descriptive analysis of malaria cases and controls from Acre State, Amazon region. Zilotto M, Ellwanger JH, Dombrowski JG, Marinho CRF, Pontillo A, Chies JAB. Genet Mol Biol. 2026 Jan 16;48(4):e20250056. doi: 10.1590/1678-4685-GMB-2025-0056.

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An NLRP3 Variant Protects Against Severe COVID-19: An Unexpected Contribution of Inflammasome Genetics in SARS-CoV-2 Infection. Paulino LM, Leal VNC, Santiago WMS, Donanzam DFA, Ledesma CRS, Bertelli MFS, Fava WS, Latini ACP, Pontillo A, Venturini J. Int J Immunogenet. 2026 Feb;53(1):23-29. doi: 10.1111/iji.70021.

2025

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Impact of NLRP1 Met1154Val and IL1B variants on gestational malaria: an unexplored role of NLRP1 in inflammasome activation by Plasmodium spp. Leal VN, Ribeiro JA, Marra LG, Rio AT, Reis EC, Wunderlich G, Dombrowski JG, Marinho CRF, Pontillo A. J Pathol. 2025 Sep 9

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Transcriptomic and Immunopathological Profiles of Inflammasomes in Different Clinical Forms of American Cutaneous Leishmaniasis.

Alcântara LDS, Campos MB, Lima ACS, Pontillo A, Souza KBDS, Ferreira AF, Camargo CP, Oba-Shinjo SM, Laurenti MD, Corbett CEP, da Matta VLR, Nakaya H, Silveira FT, Gomes CMC. Microorganisms. 2025 Apr 24;13(5):980.

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Integrated Genetic and Cellular Analysis Reveals NLRP1 Activation in CD4+ T Lymphocytes During Chronic HIV Infection.

Leal VNC, Roa MEGV, Cantoni JS, Reis ECD, Lara AN, Pontillo A. Immunol Invest. 2025 Fev 54(2):147-166

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