top of page

Recent publications

2025

Updating the frequency of CCR5Δ32 in Brazil: Descriptive analysis of malaria cases and controls from Acre State, Amazon region. Zilotto M, Ellwanger JH, Dombrowski JG, Marinho CRF, Pontillo A, Chies JAB. Genetics and Molecular Biology in press

An NLRP3 Variant Protects Against Severe COVID-19: An Unexpected Contribution of Inflammasome Genetics in SARS-CoV-2 Infection. Paulino LM, Leal VNC, Santiago WMS, Donanzam DFA, Ledesma CRS, Bertelli MFS, Fava WS, Latini ACP, Pontillo A, Venturini J.Int J Immunogenet. 2025 Oct 27:e70021. 

Impact of NLRP1 Met1154Val and IL1B variants on gestational malaria: an unexplored role of NLRP1 in inflammasome activation by Plasmodium spp. Leal VN, Ribeiro JA, Marra LG, Rio AT, Reis EC, Wunderlich G, Dombrowski JG, Marinho CRF, Pontillo A. J Pathol. 2025 Sep 9

Transcriptomic and Immunopathological Profiles of Inflammasomes in Different Clinical Forms of American Cutaneous Leishmaniasis.

Alcântara LDS, Campos MB, Lima ACS, Pontillo A, Souza KBDS, Ferreira AF, Camargo CP, Oba-Shinjo SM, Laurenti MD, Corbett CEP, da Matta VLR, Nakaya H, Silveira FT, Gomes CMC. Microorganisms. 2025 Apr 24;13(5):980.

Integrated Genetic and Cellular Analysis Reveals NLRP1 Activation in CD4+ T Lymphocytes During Chronic HIV Infection.

Leal VNC, Roa MEGV, Cantoni JS, Reis ECD, Lara AN, Pontillo A. Immunol Invest. 2025 Fev 54(2):147-166

2024

BTK and MMP9 regulate NLRP3 inflammasome-dependent cytokine and NET responses in primary neutrophils.

Leal VNC, Bork F, Tortola MM, Guilleaume JV, Greve CL, Bugl S, Danker B, Grimbacher B, Pontillo A, Weber ANR.

J Allergy Clin Immunol. 2024 Nov 13:S0091-6749(24)01186-2. (2025 Feb;155(2):569-582)

Analysis of Complement Factor H gene polymorphisms and their association with clinical manifestations of leptospirosis.

Santiesteban-Lores LE, Midon LM, Franco T, de Oliveira LM, Hibi S, Chiani Y, Meneses G, De Francesco Daher E, Fonseca DM, Pontillo A, Isaac L.  Immunogenetics. 2024 Nov 30;77(1):4.

Role of C-C chemokine receptor type 5 in pathogenesis of malaria and its severe forms.

Ziliotto M, Ellwanger JH, Kulmann-Leal B, Pontillo A, Chies JAB.  Int J Immunogenet. 2024 Oct 25.

Unexplained fever with consumptive syndrome in the elderly: two cases of VEXAS syndrome with inflammasome dysregulation.

Mendonça LO, Leal VNC, Roa MEGV, Barros SF, Kalil J, Pontillo A.  Clin Exp Immunol. 2024 Oct 16;218(2):213-220.

Distinctive Inflammasome Response to Hymenoptera Venoms in Allergic Individuals.

Yamada SM, Mendonça LO,Eleuterio BP, Cambui RAG, Roa MGV,  Oliveira LAT, Castro PLM, Watanabe AS, Castro FFM, Pontillo A  Arquivos de Alergia, Asma e Imunologia 2024​​

bottom of page